Scientific research

Scientific articles

Published articles relating to research around IQoro®, and the results of therapy based on its use. 

  • Some articles are published with 'open access´. For example articles #6 and #7 have been published openly and maybe spread freely.

     

  • Articles which are not "open access" are available at cost when downloaded. Most healthcare professionals will have access to these journals, for example via their hospital library.

     

  • Articles submitted (submitted but not published) may be found in the list above the scientific articles, but the abstract may not be made public before the article is published.

 

Articles

Art. # 1 – Intervention study of orofacial regulation therapy combined with palate plate
Art. # 2 – Validation of the lip force meter, including the lowest normal value for lip strength, or more correctly the strength in the buccinators mechanism, calculated using the Muppy oral screen.

Art. # 3-12, 16 (published) + Art. # 15, 17, 18 (in progress) – Intervention study with IQoro®.
Several studies were made in secret before the patents for, and registered mark of, IQoro® were approved. For this reason the product name or pictures of the device could not be published, instead the generic description ‘oral screen’ was used.

Art. # 1, 3-5, 11, 12, 14, 16, 17 – Studies of oropharyngeal dysphagia.

Art. # 3 – After 5 to 8 weeks’ training with IQoro® 97 % of patients were improved, of which 66 % recovered a normal swallowing function, this being independent of whether treatment was started soon after the stroke, or later.

Art. # 4 – Discovered a significant correlation between lip force (LF) and swallowing capacity (SC) amongst patients with stroke (p = 0.012), but not amongst healthy subjects. LF was independent of age amongst healthy subjects, but SC reduced with increased age (p < 0.0001), although not to a pathological level. A regression analysis shows that the variation in SC was affected by LF and age to an extent of 73 %.

Art. # 5 – After 13 weeks of training with IQoro® (30 sec x 3 times per day) 71 % of stroke patients regained a normal swallowing function compared with patients that trained with a palate plate (30 min x 3 times per day). This positive effect remained, as seen at the long term checkup, 18 months after training ceased.

Art. # 6, 7, 8 – Studies of facial dysfunction and treatment show three* significant improvements after 12 weeks training with IQoro®; and that the effect remained 18 months later in articles 7 and 8.  This positive effect with IQoro® was seen to be irrespective of whether the treatment started soon after stroke, or several years later.

Art. # 9, 10 – Studies of patient with esophageal dysphagia incl. misdirected swallowing, reflux, etc. for averagely 4 years (range 1-28 years) shows three* significant improvements after 6 to 8 months training with IQoro® 30 sec x 3 times per day. Training was required for several months where patients have had their difficulties for many years. Continued maintenance training two times a day, preferably before mealtimes, is probably required for best effect.

Art. # 11 – Studies of postural control, separate orofacial muscle groups, PEG-fed shows three* significant improvements in postural control, orofacial muscles, oro-pharyngeal dysphagia, and that the 5 PEG-fed patients could eat and drink and have their PEGs removed after 13 weeks’ training with IQoro®. This applied to 4 of 5 patients, the remaining patient having the PEG removed later. The effect remained as shown at the long-term checkup 18 months later.

Art. # 5, 7, 8, 11, 12, 14, 16, 17 – Studies which include long-term checkups.
Art. # 12-15, 17-18 – Not yet published.

Art. # 16 - SOFIA (Swallowing function, Oral health and Food Intake in old Age) – a national intervention study of training with IQoro®, short-term residents in care homes for the elderly in five counties in Sweden. The Swedish universities in Umeå, Örebro and Karlstad are involved with three Ph.D. students - a speech therapist, nurse and dental hygienist. More studies will be published.

 

 

Patent (# 1350314-9) + CE mark on neuromuscular excerciser IQoro®.

Thesis:
Hägg M. Sensory motor brain plasticity in stroke patients with dysphagia. A methodological study on investigation and treatment. Faculty of Medicine, Uppsala University, 2007. Thesis
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1. (Included in thesis, Paper I) Hägg M. Larsson B. Effects of Motor and Sensory Stimulation in Stroke Patients with Long-lasting Dysphagia. Dysphagia 19:219-230, 2004
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2. (Included in thesis, Paper II) Hägg M, Olgarsson M. Anniko M. Reliable Lip force measurement in healthy controls and in patients with stroke: A methodological study. Dysphagia 2: pp291-296, 2008.
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3. (Included in thesis, Paper IV) Hägg M, Anniko M. Lip muscle training in stroke patients with dysphagia. ActaOto-Laryngologica, 128 (9): pp1027-1033, 2008.
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4. (Included in thesis, Paper III) Hägg M, Anniko M. Influence of lip force on swallowing capacity in stroke patients and in healthy subjects. ActaOto-Laryngologica 130: pp1204-8, 2010.
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5. Hägg M, Tibbling L. Longstanding effect and outcome differences of palatal plate and oral screen training on stroke-related dysphagia. The Open Rehabilitation Journal, 2013, 6, pp 26-33
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6. Hägg M.,Tibbling L. Four-quadrant Facial Function in Dysphagic Patients after Stroke and Healthy Controls. Neurology Research International Volume 2014, Article ID 672685,
5 pages, http://dx.doi.org/10.1155/2014/672685
Open access: http://www.hindawi.com/journals/nri/2014/672685/
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7. Hägg MK., Tibbling LI. Effects on facial dysfunction and swallowing capacity of intraoral stimulation early and late after stroke. NeuroRehabilitation. 2015;36 (1):101-6. doi: 10.3233/NRE-141197. PMID: 25547771
Open access: http://content.iospress.com/download/neurorehabilitation/nre1197?id=neurorehabilitation%2Fnre1197
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8. Hägg M., Tibbling L. Effect of oral IQoro® and palatal plate training in post-stroke, four-quadrant facial dysfunction and dysphagia: A comparison study. Acta Otolaryngol. 2015 Sep;135(9):962-8. doi:10.3109/00016489.2015.1042043. Epub 2015 May 7. PMID: 25947252
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9. Hägg M, Tibbling L, Franzén T. Effect of IQoro® training in hiatal hernia patients with misdirected swallowing and esophageal retention symptoms
Acta Otolaryngol. 2015 Jul;135(7):635-9. 
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10. Hägg M, Tibbling L, Franzén T. Esophageal dysphagia and reflux symptoms before and after oral IQoro® training. World J Gastroenterol 2015; 21(24): 7558-7562
Open access: http://www.wjgnet.com/1007-9327/full/v21/i24/7558.htm
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11. Hägg M., Tibbling L. Effect of IQoro® training on impaired postural control and oropharyngeal motor function in patients with dysphagia after stroke.
Acta Otolaryngol 2016; 136 (7):742-748. DOI:10.3109/00016489.2016.1145797 http://dx.doi.org/10.3109/00016489.2016.1145797.
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12. Hägg M., Tibbling L. Meal observation test for treatment assessment of stroke-related dysphagia.
 

13. Hägg M., Pettersson M., Thorén C., McAllister A. Lip force in healthy children.
 

14. Oral Screen training in patients with dysphagia after stroke – a prospective randomized open-label study with blinded evalutators This study is conducted together with Hudiksvalls hospital and Norrlands University hospital in Sweden.
 

15. Franzén T., Tibbling L., Hägg M. Overweight is an overrated risk in symptomatic hiatal hernia patients. IQoro® is used in training.

16. Hägglund P., Olai L., Ståhlnacke K., Persenius M., Hägg M., Andersson M., Koistinen S., Carlsson E., Study protocol for the SOFIA project: Swallowing function, Oral health, and Food Intake in old Age: a descriptive study with a cluster randomized trial. BMC Geriatrics 2017, 17:78. DOI 10.1186/s12877-017-0466-8
Open acess: pdf
 

17. DESIRE – A two-centre intervention study with IQoro® of stroke survivors with dysphagia. A collaboration with the Medical Clinic and Speech Therapy Unit at Danderyds hospital in Stockholm.
 

18. Snoring, Apnoea study

 

 

Bibliography

 

  • Hägg M. Beneficial Effects of Motor and Sensory Stimulation in Stroke Patients with Dysphagia. Practices in Orofacial Therapy, ISBN 951-29-1930-3, 2001.

 

  • Hägg M. My Role as a Dentist in the Team at the Speech & Swallowing Centre, Gäv­leborg County Council. Practices in Orofacial Therapy, ISBN 951-29-1930-3, 2001.

 

  • Hägg M. Normal Eating Development. Practices in Orofacial Therapy, ISBN 951-29-1930-3, 2001.

 

  • Hägg M. Orofacial regulation therapy in combination with Bensow palatal plate for pa­tients with cerebral palsy. Practices in Orofacial Therapy, ISBN 951-29-1930-3, 2001.

     

  • Carlsson E, Hägg M. Foods and Dietary supplements in the prevention and treatment of disease in older adults. Kapitel: Care for stroke patients with eating difficulties. 
    Co-author Dr. Phil. Eva Carlsson, Manager of development and  research tutor,  nurse, Örebro County health Authority and the Institute for health science and medicine, Örebro university. Published 2015.

 

Other published articles

(Articles are in Swedish, the following is a translation of the articles’ titles into English)

 

  • Hägg M. A new, cost-effective and simple treatment of swallowing difficulties. Svensk ÖNH-Tidskrift Volym 16, Nr 1-2, 2009

    Hägg M. En ny kostnadseffektiv och enkel behandling av sväljsvårigheter. Svensk ÖNH-Tidskrift Volym 16, Nr 1-2, 2009

 

  • Hägg M. Swallowing difficulties amongst patients with whiplash injuries -  an area of ignorance. Dysfaginytt, Årg 18, Nr 3, 2009

    Hägg M. Sväljsvårigheter hos Whiplashskadade – stor okunskap råder. Dysfaginytt, Årg 18, Nr 3, 2009

 

  • Hägg M. Dentists can be an important resource against swallowing problems, NFH Bulletinen Nr 2, 2008

    Hägg M. Tandläkare kan vara en resurs vid sväljningsproblem, NFH Bulletinen Nr 2, 2008

 

  • Hägg M. Dentists can help patients with swallowing handicaps. Tandläkartidningen Årg 100, Nr 11, 2008

    Hägg M. Tandläkare kan hjälpa sväljningshandikappade.Tandläkartidningen Årg 100, Nr 11, 2008

 

  • Hägg M. The brain reorganised via the mouth, to help swallowing handicapped patients. Sjukhus-tandläkartidningen, Årg 33, Nr 2, 2008

    Hägg M. Via munnen reorganiseras hjärnan och hjälper sväljningshandikappade. Sjukhus-tandläkartidningen, Årg 33, Nr 2, 2008

 

  • Hägg M, Tibbling Grahn L. Downs syndrome. Treatment with emphasis on drooling, swallowing, speech and bite function. Dysfaginytt, 2003

    Hägg M, Tibbling Grahn L. Downs syndrom. Behandling med tonvikt på dregling, sväljning, tal och bettfunktion. Dysfaginytt, 2003

 

  • Hägg M. Case Studies – Stroke och LKG defects. Tandläkartidningen, 2000

    Hägg M. Case Studies – Stroke och LKG-defekter. Tandläkartidningen, 2000

 

  • Hägg M. Stroke-Dysphagia. European Study Group for Dysphagia and Globus, October Page 89, 1998

    Hägg M. Stroke-Dysphagia. Eurpean Study Group for Dysphagia and Globus, October Page 89, 1998

 

  • Hägg M. Dysphagia. Sjukhustandläkartidningen, 1998

    Hägg M. Dysfagi. Sjukhustandläkartidningen, 1998

 

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